Right now, January/2020 is the cheapest time of year to fly to Manchester. You will pay the most in November/2019.
Lufthansa, Virgin Atlantic and United fly direct between the United States of America and Manchester.
TAP AIR PORTUGAL is the cheapest airline to fly to Manchester from the United States of America.
Singapore Airlines is the best airline to fly from the United States of America to Manchester. Lufthansa is the best for direct flights. The best budget airline is Eurowings.